Mucormycosis Case Study: What Happens When Contract Black Fungus And The Symptoms

What is mucormycosis?

Mucormycosis is any fungal infection caused by fungi in the order Mucorales. Generally, species in the Mucor, Rhizopus, Absidia, and Cunninghamella genera are most often implicated.

Common sources of infections are from soil, damp walls on old buildings etc.

Mucormycosis is a very rare infection. It is caused by exposure to mucor mould which is commonly found in soil, plants, manure, and decaying fruits and vegetables. “It is ubiquitous and found in soil and air and even in the nose and mucus of healthy people,”

It affects the sinuses, the brain and the lungs and can be life-threatening in diabetic or severely immunocompromised individuals, such as cancer patients or people with HIV/AIDS.

Can steroids reduce this infection?

Steroids reduce inflammation in the lungs for Covid-19 and appear to help stop some of the damage that can happen when the body’s immune system goes into overdrive to fight off coronavirus. But they also reduce immunity and push up blood sugar levels in both diabetics and non-diabetic Covid-19 patients.

If you see Black Fungal Disease Symptoms you should immediately contact an  experienced doctor. You need to be careful to avoid this disease. You can suffer from this disease due to exposure to Fungus spores in the air.

Due to not being cautious at the right time, these fungal spores can go inside your body and damage the lungs. Between December and January in Mumbai, Bangalore, Hyderabad, Delhi and Pune, patients with this disease started reporting.

Types of mucormycosis

  • Rhinocerebral (sinus and brain) mucormycosis is an infection in the sinuses that can spread to the brain. This form of mucormycosis is most common in people with uncontrolled diabetes and in people who have had a kidney transplant.
  • Pulmonary (lung) mucormycosis is the most common type of mucormycosis in people with cancer and in people who have had an organ transplant or a stem cell transplant.
  • Gastrointestinal mucormycosis is more common among young children than adults, especially premature and low birth weight infants less than 1 month of age, who have had antibiotics, surgery, or medications that lower the body’s ability to fight germs and sickness. 9-10
  • Cutaneous (skin) mucormycosis: occurs after the fungi enter the body through a break in the skin (for example, after surgery, a burn, or other types of skin trauma). This is the most common form of mucormycosis among people who do not have weakened immune systems.
  • Disseminated mucormycosis occurs when the infection spreads through the bloodstream to affect another part of the body. The infection most commonly affects the brain and can affect other organs such as the spleen, heart, and skin.

Black fungal in covid 19 Situation

The number of patients reporting this disease in the hospital is higher than those who suffered from corona about 10–15 days ago. In about 2 months, 2 cases have been registered for this Black Fungus Infection, which attacks inside the ears, nose, and throat. Out of which, in 11 cases, the patients had to lose one eye and 5 patients died.

What happens when mucormycosis symptoms are found?

Warning signs include pain and redness around the eyes or nose, with fever, headache, coughing, shortness of breath, bloody vomits, and altered mental status. According to the advisory, infection with mucormycetes should be suspected when there is

Symptoms of rhinocerebral (sinus and brain) mucormycosis include:

  • One-sided facial swelling
  • Headache
  • Nasal or sinus congestion
  • Black lesions on nasal bridge or upper inside of mouth that quickly become more severe
  • Fever

Symptoms of pulmonary (lung) mucormycosis include:

  • Fever
  • Cough
  • Chest pain
  • Shortness of breath

Cutaneous (skin) mucormycosis can look like blisters or ulcers, and the infected area may turn black. Other symptoms include pain, warmth, excessive redness, or swelling around a wound.

Symptoms of gastrointestinal mucormycosis include:

  • Abdominal pain
  • Nausea and vomiting
  • Gastrointestinal bleeding

Disseminated mucormycosis typically occurs in people who are already sick from other medical conditions, so it can be difficult to know which symptoms are related to mucormycosis. Patients with disseminated infection in the brain can develop mental status changes or coma.

Risk factors

Predisposing factors for mucormycosis include AIDS, uncontrolled diabetes mellitus, cancers such as lymphomas, kidney failure, organ transplant, long-term corticosteroid and immunosuppressive cirrhosis, energy malnutrition, and deferoxamine therapy.[medical citation needed] Despite this, however, there have been cases of mucormycosis reported with no apparent predisposing factors present.

Corticosteroids are commonly used in the treatment of COVID-19 and reduce damage caused by the body’s own immune system during coronavirus infection. They are immunosuppressants and increase blood sugar levels in both diabetics and non-diabetic patients. It is thought that both these effects may contribute to cases of mucormycosis.

What’s the mucormycosis treatment?

While it is treated with antifungals, mucormycosis may eventually require surgery. Doctors have said that it is of utmost importance to control diabetes, reduce steroid use, and discontinue immunomodulating drugs. 

To maintain adequate systemic hydration, the treatment includes infusion of normal saline (IV) before infusion of amphotericin B and antifungal therapy, for at least 4-6 weeks.

Prevention

Use masks if you are visiting dusty construction sites. Wear shoes, long trousers, long-sleeved shirts, and gloves while gardening. Maintain personal hygiene including a thorough scrub bath.

Corona vaccines

  • Pfizer Vaccine
  • AstraZeneca Vaccine
  • Moderna Vaccine
  • Sputnik Vaccine
  • Covishield vaccine
  • Covaxin Vaccine
  • DRDO Anti Covid Drug 2G

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